Abstract The use of herbs to treat disease is almost universal among non-industrialized societies, and is often more available, accessible and affordable than purchasing expensive modern pharmaceuticals. Laggera aurita is a widely used medicinal plant in African countries like Nigeria, Senegal, Tanzania and Ghana. The leaves are the part of the plant reported to be most commonly used for medicinal purposes, although the plant can be used whole or pulped up. This paper seeks to examine the analgesic and anti inflammatory effects of the crude and n-hexane defatted portion of the aerial part of Laggera aurita Linn. using formalin induced pain and egg albumin induced inflammation in rats and as well as to evaluate its phytoconstituents. The results of the phytochemical evaluation of the extracts of the aerial part of Laggera aurita in revealed the presence of alkaloids, flavonoids, saponins, cardiac glycosides, terpenoids and tannins. The results of the pharmacological studies carried out revealed that, the crude extract showed a significant protection against inflammation and pain while the n-hexane defatted portion of the aerial part of laggera aurita posses lower activity against inflammatory and pain.
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