Abstract Gibberellins play an important role in inducing anthesis during the vegetative growth stage in many species, including leafy vegetables such as lettuce. This phenomenon known as bolting, affects severely the yield and quality of lettuce due to stem elongation and is stimulated by both high temperatures and endogenous metabolism of gibberellic acid (GA). The […]
A Quantum Chemical Analysis of the Relationships between Electronic Structure and the inhibition of Botulinum Neurotoxin serotype A by a series of Derivatives possessing an 8-hydroxyquinoline core
Abstract A formal analysis of the relationships between electronic structure and inhibition of the Botulinum neurotoxin serotype A by a series of derivatives possessing an 8-hydroxyquinoline core was carried out. The wave functions were calculated at the B3LYP/6-31G(d,p) level after full geometry optimization. A statistically significant equation relating five specific local atomic indices with inhibitory […]
A Effect of storage temperature on Hydroxymethylfurfural contents in apple juice
Abstract Hydroxymethylfurfural (HMF) is formed in foods which especially contain sugar if stored at improper temperatures or incurred heat treatment at high temperatures during production. For this purpose, in the markets of İstanbul, samples of apple juice from three different companies were randomly collected for the analysis of hydroxylmethylfurfural (HMF) in apple juice. HMF of […]
Preliminary Pharmaceutical Constituents of Crude Solvent Extracts of Flower and Stalk of Male Carica papaya
Abstract Qualitative and quantitative phytochemical screening of flower and stalk of male Carica papaya indicated the presence of these phytocompounds: alkaloids 0.53±0.01%flavonoids 0.86±0.02%, saponins 0.37±0.02%, tannins 2.06±0.01%, terpenoid 0.21±0.01%, steroid 0.08±0.01% and cardiac glycoside 1.87±0.02%. The ten fungi investigated in this research are: Aspergillus niger, Microsporum gypseum, Candida albican, Aspergillus flavus, Fusarium verticilloids, Aspergillus parasiticus, […]
Dissecting the drug-receptor interaction with the Klopman-Peradejordi-Gómez (KPG) method. I. The interaction of 2,5-dimethoxyphenethylamines and their N-2-methoxybenzyl-substituted analogs with 5-HT1A serotonin receptors
Abstract We studied the relationships between electronic structure and 5-HT1A receptor binding affinity of a group of 2,5-dimethoxyphenethylamines and their N-2-methoxybenzyl-substituted analogs. The novelty of this study is that we analyzed four hypothesis about the mode of binding, leading to four different common skeletons. For all cases statistically significant equations were obtained, each one leading […]
In silico Pharmacokinetic and Toxicity study of Some Selected Antidepressant Drugs
Abstract Major depressive disorders affect the general health and reduce the life quality. The treatments approaches are used to treat major depressive disorders are counselling and antidepressant medication. Due to occurrence of serious but low adverse events, there is essential need to design and develop new drug with lesser toxic and higher potency. In this […]
GC-MS and Molecular Docking Studies for Identification of Anti-malarial Compounds in Agbo-Iba PMII-a Polyherbal Formulation
Abstract Malaria prevalence is one of the life-threatening diseases responsible for more deaths around the world than any other parasitic disease. Due to the outbreak of strains that show resistance to the current synthetic anti-malarial arsenal, a large focus has been directed to structure based drug designing. The present study investigated the anti-malarial active constituents […]
Gaseous phase ionic formation enthalpy for 3-cyanopyridinecoordination compounds by modified forms of Kapustinskii equation
Abstract In the present work, it is shown that modified forms of Kapustinskii equation can be successfully employed to calculate the gaseous phase ionic formation enthalpy for coordination compounds, considering the reaction: M(g)2+ + 2Br–(g) + n3-cyanopy(g) → [MBr2(3-cyanopy)n](g); cyanopy = cyanopyridine. The calculated ionic formation enthalpy (ΔfIHθ) values are compared with experimental (calorimetric) values […]
Green Synthesis of Iron Nanoparticles from the Solanum torvum Flower Extract and their Antibacterial Activity
Abstract The green synthesis of nano particles involving plant extract has attracted the attention of researchers. In the present research program, the morphology of Iron nanoparticles was confirmed by Scanning Electron microscopy (SEM). We are reporting a novel biological approach for the formation of Iron nanoparticles using solanum torvum flower extract. Copper sulphate was made […]
The contents and Pharmacological Importance of Corchorus capsularis: A Review
Abstract Seeds of Corchorus capsularis contained cardiac glycosides, corchorin, corchortoxin helveticoside, corchoroside A and B, biosides, olitoriside, erysimoside, strophantidol glycosides, oliogosaccaride and olitoriside; while leaves contained flavonoids, triterpenes, saponins, glucoside, capsularin steroids and many other secondary metabolites. The pharmacological studied revealed that te plant possessed cardiac, antioxidant, antiinflammmatory, analgesic, antipyretic, antimicrobial, insecticidal and many other […]